Immunity Project

Peer reviewed article published in Vaccine

Return to blog home | Posted in: Blog on Jun 16, 2014 by Naveen Jain

Over the weekend we learned that Vaccine published our article on eliciting cytotoxic T-lymphocyte responses from synthetic vectors containing one or two epitopes in a C57BL/6 mouse model using peptide-containing biodegradable microspheres and adjuvants.  In layperson terms, this article covers the work we did in partnership with Microsoft Research to show that our biodegradable microsphere based vaccine can elicit an immune response in mice.  Download a PDF of our article or view it online at Science Direct.

This is a big step forward for us.  Our mission at Immunity Project is to develop a free HIV vaccine.  In order to do this we need to prove that our experimental data supports our approach every step of the way.  A great way for us to do this is to publish our work in a respected peer reviewed journal such as Vaccine.

Thank you to the team at Vaccine for giving us great feedback and for accepting our article for publication.  We would also like to thank Darrell Irvine of the Ragon Institute for helping us review previous research in the area, Nicole Frahm of the Fred Hutchinson Cancer Research Center for immunochemistry advice, Dan Barouch of the Beth Israel Hospital for his interest and support, Niraj Patil for assistance with illustration preparation, Craig Rouskey for helpful comments and Jonathan Carlson of Microsoft Research who helped review the manuscript.

And thank you to all of our pioneers.  None of this would be possible without your guidance and support.

If you have any questions about our article, please don’t hesitate to email us at  We would love to hear from you.  Our next step is to continue our human blood in vitro experiments and publish our results as soon as we can.  We’re honored to have your support and look forward to sharing the results of our new experiments with you.  Thank you again for helping us make Immunity Project happen.

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